CORE Workshop - Chirality in Practice

CORE Workshop - Chirality in Practice

What, When & Where

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The CORE Workshop - Chirality in Practice took place on 20-24 May 2019 in Groningen, the Netherlands hosted by Beneficiary Partner, Syncom. All Early Stage Researchers (ESRs) and their supervisors, together with representatives of the associate partner organisations, external experts, the project manager and the project assistant, met to discuss the CORE project.

This workshop consisted of a scientific component in which the ESRs were trained on Chiral Synthesis. In addition, the industrial component of the workshop covered how the workshop theme relates to industry (for instance a seminar on a specific industrial challenge by one of the industrial partners):

  • A presentation of how a quotation is made for work including purchase of chemicals, search of literature for procedures, time allotment, risk management (Richard Kellogg)
  • Chirality, business and Viedma ripening (Dr. Bernard Kaptein, Innosyn)
  • A tour of the Syncom facilities (Mark Hamminga, Dr. Michel Leeman and Richard Kellogg)

Furthermore, the workshop included discussion sessions on developing the CORE Toolbox.

The ESRs had their own private evaluation session to discuss general successes, strengths and weaknesses of the Network to date. The outcomes of this session were reported to the CORE Steering Committee, who will act on the reported issues.

In addition, the workshop contained a transferrable skills component. 

The workshop timings for ESR training were roughly over the two and a half days (Monday, Thursday and half day on Friday, usually finishing after lunch). The Tuesday and Wednesday were set aside for the network – ESR presentations and meetings, this was when the Supervisors, Associate Partners and External Experts were invited to attend.

A detailed agenda is presented below.


Early Stage Researchers (ESRs), their supervisors and colleagues, representatives of the partner organisations, external experts, the project manager and project assistant were invited to participate in this event.


All ESR participants were expected to be present on Monday 20 May 2019 at 08:45hrs until Friday 24 May 2019 at 12:00hrs.

All Supervisors, Associate Partners and External Experts were invited to be present on Tuesday 21 and Wednesday 22 May 2019.


To travel from Schiphol airport to Groningen takes around 2 hours and 30 minutes by train. Trains leave every 30 minutes. One train is direct whereas a brief change is required for the other. [Full train schedule will be sent together with info how to get from train station to hotel in due course].

ESRs and Supervisors made their own hotel arrangements.  

Recommended hotels included:

City Hotel Groningen, Gedempte Kattendiep 25, 9711 PM Groningen www.cityhotelgroningen.com

Best Western Hotel Groningen Centre, Radesingel 50, 9711 EK Groningen  

The Student Hotel, Boterdiep 9, 9712 LH Groningen www.thestudenthotel.com/groningen 

The preferred recommendation was City Hotel Groningen. The other two were more than acceptable and located right in the centre of Groningen, which is not a large city. The Student Hotel is a regular hotel rather than one specially for students. For all hotels, it is not more than a 15 minute walk from the train station. One can take a taxi, of course.  Prices run about euro 90-100 euro/night. Each hotel has cancellation policies. It is wise to book in plenty of time because there are other conferences taking place in Groningen at the same time.

People who come with a car should look at the website of the hotel to get recommendations for parking. There are quite a few (expensive) parking garages in Groningen.


Late Tuesday afternoon (21 May 2019) guided tour through centre of Groningen and dinner at Café de Sleutel.http://cafedesleutel.nl/

Detailed draft agenda

Location: Syncom BV, Kadijk 3, Groningen 9747 AT

Meetings took place in the building located at Mudden 12. In the Mudden building, most meetings were held in the main lecture room (collegezaal) on the ground floor. Most other meetings were held in other rooms within the Mudden building.


Monday 20 May 2019

08:45                  Welcome Richard Kellogg; Introduction Joop ter Horst

09:00-10:00        Dr. Wim L. Noorduin, AMOLF, “Physical Chemical Routes to Single Handedness”

10:00-11:30        Break and Tour of Laboratory Facilities, Mr. Mark Hamminga, Dr. Michel Leeman and Richard Kellogg

11:30-12:30        Dr. Robert Hof, Chief Operating Officer, MercachemSyncom, “MercachemSyncom and Our Role in Drug Discovery”

12:30-14:00        Lunch

14:00-15:00        Dr. Bernard Kaptein, Innosyn Laboratories, “Chirality in Practice”

15:00-15:30        Break

15:30-16:15        Richard Kellogg, "Science, Business and the Hard Facts of Life"

16:15-17:15         IP / Entrepreneurship Session 1 (Theory)

Return to hotel; everyone was free for the evening. Groningen has many restaurants ranging from reasonably priced to expensive.

Tuesday 21 May 2019

08:45-09:00       CORE Toolbox Introduction

09:00-11:00       CORE Toolbox Presentations WP3 x 4 (20 min plus 5/10min Q&A per person)

  • ESR4: Brigitta Bodak, ETH Zurich (Swiss Federal Institute of Technology in

Zurich), Switzerland (ETH)

  • ESR3: Francesca Cascella, Otto-von-Guericke University Magdeburg, Germany (OVGU)
  • ESR2: Johannes Hoffmann, University of Strathclyde, Scotland UK (USTRATH)
  • ESR1: Shashank Bhandari, Otto-von-Guericke University Magdeburg, Germany (OVGU)

11:00-11:30        Break

11:30-12:30        CORE Toolbox Presentations WP4 x 2 (20 min plus 5/10min Q&A per person)

  • ESR9: Carola Tortora, Friedrich - Alexander University Erlangen - Nürnberg, Germany (FAU)
  • ESR8: Francesca Breveglieri, ETH Zurich (Swiss Federal Institute of Technology in Zurich), Switzerland (ETH)

12:30-14:00        Lunch for ESRs and in parallel Supervisory Board

14:00-15:00        Dr. Luc van Hijfte, MercachemSyncom, “A Neglected Compound, for a Neglected Disease: TB or not TB"

15:00-16:00        Free time

16:00-17:30        Guided Tour of Groningen (Leaving from tourist office at main market place, Grote Markt)

18:00                  Dinner in Groningen, Café de Sleutel, Noorderhaven 72, 9712 VM Groningen (Tel: 050-3181454, E: info@cafedesleutel.nl)

Wednesday 22 May 2019

09:00-10:30        CORE Toolbox Presentations WP4 x 3 (20 min plus 5/10min Q&A per person)

  • ESR7: Ryusei Oketani, University of Rouen, France (UR)
  • ESR6: Giulio Valenti, SYNCOM, The Netherlands
  • ESR5: Giuseppe Belletti, Radboud University Nijmegen, Netherlands (RUN)

10:30-11:00        Break

11:00-12:30        CORE Toolbox Presentations WP5 x 3 (20 min plus 5/10min Q&A per person)

  • ESR15: Ghufran ur Rehman, University of Manchester, UK (UM)
  • ESR14: Raghunath Venkatramanan, University of Strathclyde, Glasgow, UK (USTRATH)
  • ESR13: Maxime Charpentier, University of Strathclyde, Glasgow, UK (USTRATH)

12:30-13:30        Lunch and Networking with Associate Partners and External Experts

13:30-15:00        CORE Toolbox Presentations WP5 x 3 (20 min plus 5/10min Q&A per person)

  • ESR12: Lina Harfouche, University of Rouen, France (UR)
  • ESR11: Aliou Mbodji, University of Rouen, France (UR)

ESR10: Jan-Joris Devogelaer, Radboud University Nijmegen, Netherlands (RUN)

15:00-15:30        Break

15:30-16:30        Parallel Meetings of CORE Industrial Toolbox (WP3: Towards Continuous w/ Joop ter Horst, WP4: Hybrid Resolution w/ Elias Vlieg and WP5: Enabling Resolution w/ Valérie Dupray)

 Parallel meetings will take place in the following locations:-

  • Work Package 3: Office of Ton Vries
  • Work Package 4: Office of Marga Vos
  • Work Package 5: Main lecture room (collegezaal)

16:30-17:00        Toolbox Summary and Discussion

17:30-18:30        CORE Steering Committee Meeting (Beneficiary Partners only)


Thursday 23 May 2019

09:00-10:00        Dr. Michel Leeman, MercachemSyncom, “Resolution of Racemates by Crystallization”

10:00-10:15        Break

10:15-11:15        Dr. H. Meekes, Radboud University, Nijmegen, “Racemization, Deracemization and Isomerization Developments Outside of CORE”

11:15-12:15        Dr. Jean-Paul Seerden, Syncom BV, “Billion Dollar Drugs”

12:15-13:15        Lunch

13:15-14:30        IP / Entrepreneurship Session 2 (Practical)

14:30-14:45        Break

14:45-16:00        IP / Entrepreneurship Session 3 (Short Presentations)

16:00-16:30        Evaluation Session for ESRs (with Claire Scott)


Friday 24 May 2019

09:00-12:00        Presentation Skills by Artesc

12:00-13:00        Lunch

Chirality in Practice Programme v4


For any questions, please contact:

Claire SCOTT
Project Manager
CORE ITN Project, University of Strathclyde
p: +44 141 444 7198
w: https://www.strath.ac.uk/staff/scottclairems/
e: claire.scott@strath.ac.uk


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