Johannes Hoffmann
ESR2: Continuous Crystallization-enables Chiral Synthesis
Host institution: University of Strathclyde, Scotland UK (USTRATH)
Host Supervisors: Prof Joop TER HORST and Prof William KERR
Industrial toolbox research group: WP3 Continuous Resolution
Individual project research objective: Develop optimized industry-ready continuous configurations of Crystallization-enabled Chiral Synthesis.
Committee membership: Supervisory Board
Visits/Secondments: OVGU, RUN, SYNCOM
Background
Johannes started working in CORE in January 2017. He obtained his Master’s Degree in Process Engineering at the Otto-von-Guericke University of Magdeburg. Before joining the project, he worked as a research assistant at the Max Planck Institute for Dynamics of Complex Technical Systems in Magdeburg focusing on continuous resolution of enantiomers using crystallization. He will be working under Prof. H Ter Horst on continuous resolution of enantiomers using antisolventcrystallization and racemization. Therefore he will be involved in various research Projects as well as collaboration with other Universities.Research Interests
The research of Johannes Hoffmann focuses on the process aspect of continuous crystallization. During his master thesis he worked on continuous chiral separation using a fluidized bed crystallizer at the Max Planck Institute Magdeburg, leading the reconstruction of a pilot plant and researching the influence of different process parameters on the process. He now focuses on continuous chiral separation using antisolvent crystallization and racemization enabled preferential crystallization.
Contact details
johannes.hoffmann@strath.ac.uk
+44 (0)141 444 7197
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Dissemination
2019
Conference presentations
Hoffmann, Johannes , R. Venkatramanan, F. Cascella, A. Seidel Morgenstern, H. Lorenz, J. H. ter Horst (2019)Selective Sequential Crystallization of Racemic and Enantiopure Mandelic Acid at the Solution Eutectic
12th European Congress of Chemical Engineering (ECCE12), 15-19 September 2019, Florence, Italy
Hoffmann, Johannes , R. Venkatramanan, F. Cascella, A. Seidel Morgenstern, H. Lorenz, J. H. ter Horst (2019)
Selective Sequential Crystallization of Racemic and Enantiopure Mandelic Acid at the Solution Eutectic and its applicability in the pharmaceutical industry
CMAC Showcase Event, 23-24 October 2019, University of Strathclyde, Glasgow, UK
Hoffmann, Johannes , R. Venkatramanan, H. Lorenz, A. Seidel-Morgenstern and J. H. t. Horst (2019)
Serial Separation and Resolution in Eutectic Solutions
BACG 50th Annual Conference, London, 9-11 July 2019
Poster
Hoffmann, Johannes , M. Charpentier, C. Mack, C. J. J. Gerard, J. Sefcik, J. H. ter Horst (2019)Industrial Crystallization Fundamentals
CMAC Showcase Event, 23-24 October 2019, University of Strathclyde, Glasgow, UK
2018
Blog
Hoffmann, Johannes (2018)Working Cross Borders
CORE Blog
CORE Blog Post, 6 February 2018
Conference presentations
Hoffmann, Johannes , R. Venkatramanan, F. Cascella, A. Seidel-Morgenstern, H. Lorenz, J. H. ter Horst (2018)Separation of Mandelic Acid Enantiomers at Eutectic Composition by Preferential Crystallization
25th International Workshop on Industrial Crystallization (BIWIC), 6-7 September 2018, University of Rouen, France
Poster
Hoffmann, Johannes , René R. E. Steendam, Joop H. Ter Horst (2018)Controlling Crystal Chirality in Continuous Cooling and Antisolvent Crystallization of Sodium Bromate
EPSRC Centre for Innovative Manufacturing in Continuous Manufacturing and Crystallisation (CMAC) Open Day, 25-26 October 2018, University of Strathclyde, Glasgow UK
Public engagement
Hoffmann, Johannes , Maxime Charpentier (2018)Crystal Builders, 2018
Explorathon: European Researchers Night, 29 September 2018 in Riverside Museum
2017
Poster
Hoffmann, Johannes (2017)Crystal Chirality Control in Continuous Antisolvent Crystallization of Sodium Bromate
International Symposium on Industrial Crystallization (ISIC 20), 3-6 September 2017, UCD (Dublin, Ireland)
Public engagement
Hoffmann, Johannes , Joop ter Horst (2017)Chiral resolution using antisolvent crystallization
Monday 10 July 2017, Dutch Design & Synthesis lectures, Syncom BV, The Netherlands
Hoffmann, Johannes , Sudhansu Sekhar Jena, Giulio Valenti, Raghunath Venkatramanan (2017)
Crystal Builders, 2017
Explorathon: European Researchers Night, 29 September 2017 in Riverside Museum