Francesca CascellaFrancesca CASCELLA

ESR3: Continuous Enantioselective Crystallization Processes

Host institution: Otto -von- Guericke University Magdeburg, Germany (OVGU)
Supervisor:  Prof Andreas SEIDEL-MORGENSTERN
Industrial toolbox research group: WP3 Towards Continuous
Individual project research objective: To Deliver Methods and Design Rules for Continuous Preferential Crystallization Techniques
Committee membership: Training Committee
Visits/Secondments: UR, ETH, PCAS


Francesca Cascella joined the CORE-ITN in May 2017. She graduated at University of Bari ”Aldo Moro”(Italy) in Chemistry. Now she works in the Max Planck Institute for Dynamics of Complex Technical Systems of Magdeburg (Germany) focusing on the Continuous Resolution of Enantiomers by Crystallization, under the supervision of Prof. Heike Lorenz and Prof. Andreas Seidel-Morgenstern.

2017: Masters’ degree in Chemistry at University of Bari “Aldo Moro”,  “Synthesis and characterization of Cesium Lead Bromide nanoparticles for optoelectronic applications ’’

2014: Masters’ degree in Chemical Science at University of Bari “Aldo Moro”, “Synthesis of bioactive cyclopropane through activation of C-H bond in ionic liquids”.

Research Interests

Experimetal study in synthesis of organic molecules, colloidal nanoparticles, and their optical and morphological characterization.

Contact details
+49 17637615801            


back to early stage researchers




Cascella, Francesca , Ghufran ur Rehman (2020)
An Interview with Two CORE Early Career Researchers
CORE Blog post, 30 January 2020

Conference presentations

Cascella, Francesca , H. Lorenz, A. Seidel-Morgenstern (2020)
Design and Operation of Batch Crystallization Processes for Enantioseparation Purposes
Jour Fixe Crystallization Series, Virtual Presentation Through TU Dortmund, Germany, 26 June 2020


Cascella, Francesca , Carola Tortora, Christina Mai, Michael Mauksch, Andreas Seidel-Morgenstern, Heike Lorenz and Svetlana B. Tsogoeva (2020)
Speeding up Viedma Deracemization through Water catalyzed and Reactant Self‐catalyzed Racemization
ChemPhysChem Publication date (Web): 9 June 2020

Journal cover profiles

Cascella, Francesca , C. Tortora, C. Mai, M. Mauksch, A. Seidel‐Morgenstern, H. Lorenz and S. B. Tsogoeva (2020)
Cover Feature: Speeding up Viedma Deracemization through Water‐catalyzed and Reactant Self‐catalyzed Racemization
ChemPhysChem Publication Date (web): 24th August 2020

Public engagement

Cascella, Francesca , Joop ter Horst, Andreas Seidel-Morgerstern, Raghunath Venkatramanan, Heike Lorenz (2020)
EU H2020 ITN CORE: Creating Better Pharmaceutical Products for Society
CORE ITN YouTube Channel
Published online 18 June 2020



Cascella, Francesca (2019)
A Window Into Your Future
CORE Blog post, 27 February 2019


Cascella, Francesca , Erik Temmel, Andreas Seidel-Morgenstern and Heike Lorenz (2019)
Efficient resolution of racemic guaifenesin via batch preferential crystallization processes

Cascella, Francesca , A. Seidel-Morgenstern, H. Lorenz (2019)
Exploiting ternary solubility phase diagrams for resolution of enantiomers: An instructive example
Chemical Engineering & Technology

Cascella, Francesca , Erik Temmel, Matthias J. Eicke, Andreas Seidel-Morgenstern, Heike Lorenz (2019)
Resolution of Racemic Guaifenesin Applying a Coupled Preferential Crystallization-Selective Dissolution Process: Rational Process Development
Crystal Growth & Design
DOI: 10.1021/acs.cgd.8b01660 Publication Date (Web): 1 May 2019


Cascella, Francesca , Shashank Bhandari, H. Lorenz, A. Seidel-Morgenstern (2019)
Preferential Enantioselective Crystallization: experiments and modelling
IMPRS conference YCOPE 2019, 18-20 March, 2019, Max Planck Magdeburg, Germany

Cascella, Francesca , E. Temmel, A. Seidel-Morgenstern, H. Lorenz (2019)
Studies on batch preferential crystallization of an API
[Poster and flash presentation] Crystallization meeting in Bamberg, 12-13 March 2019



Cascella, Francesca (2018)
Behind the scenes of a Marie Curie PhD
CORE Blog post, 14 May 2018


Cascella, Francesca , E. Temmel , A. Seidel-Morgenstern, H. Lorenz (2018)
Fundamental Studies for Continuous Preferential Crystallization of Guaifenesin
[Winner, First Place, Best Poster Award] 25th International Workshop on Industrial Crystallization (BIWIC), 6-7 September 2018, University of Rouen, France


Cascella, Francesca (2018)
Fundamental Studies for Continuous Preferential Crystallization of Guaifenesin
First Place, Best Poster Award at the 25th International Workshop on Industrial Crystallization (BIWIC), University of Rouen, France, 6-7 September 2018

Public engagement

Cascella, Francesca , Shashank Bhandari (2018)
13th Long Night of Science
13th Long Night of Science, 2 June 2018, Max Planke Institute Magdeburg

Cascella, Francesca , Shashank Bhandari, Giuseppe Belletti, Lina Harfouche, Aliou Mbodji, Ghufran ur Rehman, Carola Tortora, Giulio Valenti, Raghunath Venkatramanan (2018)
CORE Crystal Growth Competition with Local High Schools
CORE Crystal Growth competition with local high schools (2018) France, Germany, The Netherlands, UK



Cascella, Francesca , H. Temmel, F. Cascella, H. Lorenz, A. Seidel-Morgerstern (2017)
Continuous preferential crystallization of a chiral API
24th International Workshop on Industrial Crystallization (BIWIC 2017), 27-31 August, Dortmund University