Host institution: University of Rouen, France
Supervisor: Prof Samuel PETIT and Dr Yohann Cartigny
Industrial toolbox research group: WP5 Enabling Resolution
Individual project research objective: Development of a method to identify competing solid states and phase diagram of multicomponent chiral systems.
Committee membership: Training Committee
Visits/Secondments: USTRATH, OVGU, PSE
Lina Harfouche, PhD student in the university of Rouen-France in the SMS laboratory. She obtained from the Lebanese University of Beirut a bachelor's degree in specialized chemistry, a master's degree in analytical and environmental chemistry and a master 2 in physical chemistry materials and catalysis. Her project is to develop a screening methodology to quickly and reliably determine the crystallization-based resolution possibilities of a new chiral compounds, development of methods for assessing the solid state and phase diagram by measuring solid state changes and solubilities in complex multicomponent systems of chiral compounds. Special focus will be given to racemic compounds and the effect of racemization and racemizing agents on the solubility and solid state changes. Finally, these methods will be integrated into a screening tool for the crystallization behavior of chiral compounds in complex multicomponent systems.
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