Giuseppe BellettiGiuseppe BELLETTI

ESR5: Viedma Ripening-enabled Chiral Synthesis

Host institution: Radboud University Nijmegen, Netherlands (RUN)
Supervisor:  Prof Elias VLIEG
Industrial toolbox research group: WP4 Hybrid Resolution
Individual project research objective: 
Committee membership: Dissemination Committee
Visits/Secondments: USTRATH, FAU, TC


Giuseppe holds a Master’s Degree in Chemical Sciences from the University of Ferrara, Italy. After an experience of 6 months working as a chemical engineer in a multinational company, he decided to apply as a PhD student in this network, in order to improve his skills and learn from people with high scientific backgrounds, collaborating together with the other researchers. His passion for chemistry and his curiosity brought him to choose this important step for his career. 

Research Interests

During his Master’s Thesis work, Giuseppe and the team he was working with mainly focused on the synthesis of optically active compounds and their deracemization, through the use of specific kind of enzymes as a catalysts. Those chiral compounds could be used then, in a further step, for the synthesis of some strategic pharmaceuticals. 

Contact details
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Belletti, Giuseppe , Mbjodi, Aliou and Devogelaer,Jan-Joris (2019)
Solvay workshop on “Chiral symmetry breaking at molecular level” – Brussels, 28-30 November 2018


Belletti, Giuseppe , C. Tortora, I. Mellema, P. Tinnemans, H. Meekes, F. Rutjes, S. Tsogoeva, E. Vlieg (2019)
Photoracemization‐based Viedma ripening of a BINOL derivative
Chemistry: A European Journal Publication Date (Web): 30 October 2019

Belletti, Giuseppe , Christos Xiouras, Raghunath Venkatramanan, Alison Nordon, Hugo Meekes, Elias Vlieg, Georgios D. Stefanidis, Joop H. Ter Horst (2019)
Towards Continuous Deracemization via Racemic Crystal Transformation monitored by in-situ Raman Spectroscopy
Crystal Growth & Design Publication Date (Web): 23 August 2019


Belletti, Giuseppe (2019)
Photoracemization-based Viedma ripening of a BINOL derivative
sIMMposium 2019, Radboud University, Nijmegen, 21-22 October 2019

Journal cover profiles

Belletti, Giuseppe , C. Tortora, I. D. Mellema, P. Tinnemans, H. Meekes, F. P. J. T. Rutjes, S. B. Tsogoeva and E. Vlieg (2019)
Cover Feature: Photoracemization‐Based Viedma Ripening of a BINOL Derivative
Chemistry: A European Journal Publication Date (web): 11th December 2019



Belletti, Giuseppe , Hugo Meekes, Floris P. J. T. Rutjes and Elias Vlieg (2018)
Role of Additives during Deracemization Using Temperature Cycling
Crystal Growth and Design
DOI: 10.1021/acs.cgd.8b00856 Publication Date (Web): October 2, 2018


Belletti, Giuseppe , H. Meekes, F. P. J. T. Rutjes and E. Vlieg (2018)
The role of additives during deracemization using temperature cycling
25th International Workshop on Industrial Crystallization (BIWIC), 6-7 September 2018, University of Rouen, France

Public engagement

Belletti, Giuseppe , Shashank Bhandari, Francesca Cascella, Lina Harfouche, Aliou Mbodji, Ghufran ur Rehman, Carola Tortora, Giulio Valenti, Raghunath Venkatramanan (2018)
CORE Crystal Growth Competition with Local High Schools
CORE Crystal Growth competition with local high schools (2018) France, Germany, The Netherlands, UK



Belletti, Giuseppe , Mbodji, Aliou (2017)
Summer School, Nijmegen ’17 – Teamwork is the key
CORE Blog post - 22 August 2017


Belletti, Giuseppe , Hugo Meekes, Floris P. J. T. Rutjes, Elias Vlieg (2017)
The role of additives in the deracemization of conglomerate-forming compounds using temperature cycling
Summer School on Chiral Crystallization, Resolution & Deracemization, Nijmegen, The Netherlands, July 3-6, 2017